![]() ![]() The occurrence of lacunes was correlated with the duration of diabetes mellitus and the age (OR =1.141, 95% CI: 1.102-1.180, P<0.001), while white matter hyperintensities were independently correlated only with the age (OR =1.124, 95% CI: 1.094-1.155, P<0.001). 70.4% (P=0.003), respectively, and an occurrence of white matter hyperintensities of 41.1% vs. Lacunes and white matter hyperintensities were more common in the diabetes mellitus group than in the IGT group and the Control group, with an occurrence of lacunes of 83.3% vs. Then correlation analysis and regression analysis were used to explore the correlation between diabetes with related risk factors and silent cerebral small-vessel disease. All the baseline information and diabetes-related factors, such as glycated hemoglobin level, insulin usage, etc., were collected. All patients underwent magnetic resonance imaging to investigate the silent cerebral small-vessel disease: the lacunes and the white matter hyperintensities. Totally 698 patients were included in this study, from January 2014 to December 2019, among which 270 patients were included in the diabetes mellitus group, 106 patients were included in the IGT group, and 322 patients were included in the Control group. ![]() This is a retrospective cross-sectional study. Physical as well as intellectual activity also prevents the risk of pathological aging.The present study aimed to evaluate the frequency of silent cerebral small-vessel disease, especially lacunes and white matter hyperintensities, in patients with or without the impaired glucose tolerance (IGT) and type-2 diabetes mellitus, and to characterize the diabetes-correlated factors related to silent cerebral small-vessel disease. It is known that the more time you spent in school, the more you will be protected against the disease, and the same goes for a healthy diet, such as those aimed at preventing diabetes, hypertension and cholesterol. The main purpose is to sensitize the general public, as people from disadvantaged backgrounds with limited access to education and subject to dietary deficiencies are more vulnerable to cognitive aging. We must not trivialize the warning signs.įrom the age of 50, if people complain of their memory, it is advised to test it or make an MRI. The Leenaards Memory Centre – CHUV offers "brain check-ups" integrated within the cantonal action plan. Finally, the clinical research which is translational, meaning that it establishes links between research in biology and imaging and applies the fundamental knowledge for better diagnosis and treatment of patients. Second axis: the training of young doctors, psychologists, nurses and social workers. First comes the medical care, which aims to improve the potential of the university centre as a centre of expertise, consultation and screening. Supported by The Leenaards Foundation, the Center is multidisciplinary and cooperates with three Departments of CHUV: the Department of Clinical Neuroscience, the Department of Medicine ( Geriatrics) and the University Service of Advanced Age Psychiatry. How does The Leenaards Memory Centre – CHUV function? All the effort of the Centre aims to improve care for patients and their families to prevent and alleviate the problems. The older we get, the more likely it is to accumulate these lesions. CLM also focuses on vascular dementia, linked to the accumulation of small strokes in the brain. If Alzheimer's disease is a problem in itself, representing 50% of the cases of dementia, Parkinson's disease is also addressed, as well as frontal dementia (characterized by sociopathy) that affect younger patients. The Centre mainly deals with disorders of higher brain functions: not only memory, but also those of language or the ability to make judgments. The objective of the CLM is to coordinate the activities of the network by playing a real role of reference and center of innovation. Given the scale of these diseases, the Department of Health and Social Action of the canton of Vaud has decided to create a network of four Memory Centers, including the Leenaards Memory Centre-CHUV (CLM), in the context of the cantonal program on Alzheimer. Obviously there is also a huge emotional pain. With an aging population, these disorders are becoming more common and costly, since we can be live with disease for longer. 5,000 new cases are expected to be announced in the near future in the Canton de Vaud. Dementia and memory impairment in the elderly constitute a real "silent epidemic".
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